It kind of exploded,” says Buenrostro, noting that ATAC-seq now has its own Wikipedia page. “I didn’t realize how useful it would be for people. Regions of DNA need to be tightly wound to fit inside the nucleus, and only open DNA regions can be active.īuenrostro and his colleagues developed a tool called ATAC-seq to measure these open regions of the genome, many of which don’t make proteins but regulate genetic activity. So in his graduate research at Stanford, he pivoted to developing methods for measuring these underexplored regions.ĭNA is essentially identical from cell to cell, but a kidney cell differs from a brain cell in the activity of those genes. But many of the mutated genes he found were considered junk because they didn’t direct the production of proteins. He wanted to understand the effects of the genetic mutations his machine detected.
Instead he decided to develop and collect lots of different technologies, so his company could tackle any water contamination problem it encountered.Īfter Jason Buenrostro graduated from Santa Clara University with a degree in biology and engineering, he went to work in a lab at Stanford, overseeing an $800,000 gene sequencing machine. But Bajpayee realized that it was a long way from commercial viability and any business built around this one idea was likely to fail. This year Gradiant will launch its first commercial system based on a new technology that can be installed in seawater desalination plants to increase recovery of fresh water by up to 85%.Īs a PhD student at MIT he invented a membrane-free desalination technique that Scientific American recognized as one of its annual Top 10 World-Changing Ideas.
Since then they’ve developed an extensive patent portfolio, says Bajpayee, and commercialized two more treatment technologies -one that efficiently pulls specific contaminants out of industrial wastewater so it can be reused, and another that disinfects water without the use of chemicals like bleach. They quickly found customers keen to use Govindan’s technology to extract water from fluids contaminated during the process, which reduces water requirements and minimizes how much toxic brine needs to be stored in deep disposal wells. The oil and gas industry was at the peak of the shale boom thanks to advances in fracking, where rock formations are fractured using pressurized fluids to extract oil and gas trapped inside.
And after just six years, his Boston-based company, Gradiant, has more than 200 employees and operates more than 20 treatment plants around the world.īajpayee started Gradiant with lab-mate Prakash Govindan, who like him was working on desalination techniques. Later, Manish was murdered by the trio outside the hotel, following an altercation over bill payment.Anurag Bajpayee built a one-stop shop for cleaning up the world’s most contaminated water. Police had then revealed that the three accused in the case, along with Manish had visited the bar on that fateful night. During the investigation of the case, police discovered through the CCTV footage of the hotel that Manish had been to that bar, a night prior to his death. Hotel South City's dance bar came to the limelight, after the death of Manish Anurag on October 10. The dance bar, which was sealed after the details of the murder surfaced, was reopened and raids were conducted by police after reports of its illegal operation.ĭuring the raid at the bar at Hotel South City, police seized huge quantities of alcohol and bundles of cash from the premises. Later on Saturday, Prasanna Behera was arrested along with the owner of the hotel and the bar manager. Following a probe by Additional DCP, Constable Prasanna Behera was suspended from duty as he was operating the bar on lease. The IIC was transferred for dereliction of duty for letting the dance bar, which Manish visited just before murder, operate without licence in his jurisdiction. The Inspector-In-Charge (IIC) of Tamando Police Station, Pramod Pattanayak, was transferred to DCP office for dereliction of duty. The IIC of Tamando Police Station in Bhubaneswar was transferred on Friday (Oct 22) in connection with the murder of Manish Anurag, son of senior journalist Navin Das.
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